Rats received daily injections of haloperidol (HAL, 5 mg/kg SC, or IP) or tartaric acid vehicle for 14-21 days. Four to six days after discontinuation of the daily injections, rats were given a single 5-min tail pinch (TP) test. HAL-treated rats showed significantly shorter latencies to display oral
Effects of Chronic Haloperidol and/or Clozapine on Oxidative Stress Parameters in Rat Brain
✍ Scribed by Fabiano R. Agostinho; Luciano K. Jornada; Nadja Schröder; Rafael Roesler; Felipe Dal-Pizzol; João Quevedo
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 185 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Previously, we demonstrated that serotonin-lesioned rats had an enhanced mesoprefrontal dopaminergic response to restraint stress. This study attempted to extend our knowledge regarding this serotonin/dopamine interaction by seeing if suppression of serotonin metabolism by chronic administration of
Despite multiple lines of investigation the effect of neuroleptics on glutamate-mediated neurotransmission remains controversial. To study the effects of typical and atypical neuroleptics on selected parameters of glutamate-mediated neurotransmission, male Sprague-Dawley rats were randomly assigned