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Effects of chronic administration of vanadate to the rat on the sensitivity of glycolysis and glycogen synthesis in skeletal muscle to insulin

โœ Scribed by R.A.John Challiss; Brendan Leighton; Fred J. Lozeman; Leszek Budohoski; Eric A. Newsholme


Book ID
115779658
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
561 KB
Volume
36
Category
Article
ISSN
0006-2952

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Effects of the diuretic furosemide on th
โœ G. Dimitriadis; B. Leighton; M. Parry-Billings; E. A. Newsholme ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 394 KB

The diuretic furosemide (0.5 mmol/l) impaired glucose uptake in the soleus muscle of the rat by decreasing the sensitivity of glycolysis to insulin. In addition, at higher concentrations (1.0 mmol/l) the drug inhibited the basal rate of glycolysis. It did not, however, inhibit the rate of glycogen s