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Effects of Cholesterol Feeding on the Bile Acids of Male and Female Germ-Free Rats

✍ Scribed by Guido G. PARMENTIER; Lutgart M. -J. SMETS; Gerard A. JANNSEN; Hendrik J. EYSSEN


Book ID
115119990
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
690 KB
Volume
116
Category
Article
ISSN
1432-1327

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Regulation of bile acid synthesis. II. E
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Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac