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Effects of cholesterol and temperature on the permeability of dimyristoylphosphatidylcholine bilayers near the chain melting phase transition

✍ Scribed by William V Kraske; Donald B Mountcastle

Book ID
117047887
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
205 KB
Volume
1514
Category
Article
ISSN
0005-2736

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VPDLLADLLK is a synthetic decapeptide, which shows a difference in conformation in various environments. Circular dichroism spectral studies show that it exists in an unordered conformation in the aqueous phase, and in dimyristoylphosphatidylcholine (DMPC) lipid bilayer, it exhibits an alpha-helical

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The technique of scanning densitometry was applied to a study of the effect of fatty acids on the packing and phase transition properties of dimyristolyphosphaticylchollne (DMPC). It was observed that the three fatty acids studied, i.e. palmitic, palmitoleic and behenic, had the effect of broadening