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Effects of changes in extracellular pH and potassium concentration on Kv1.3 inactivation

✍ Scribed by Sándor Somodi; Péter Hajdu; Rezső Gáspár; György Panyi; Zoltán Varga

Book ID
105946415
Publisher
Springer
Year
2008
Tongue
English
Weight
812 KB
Volume
37
Category
Article
ISSN
1432-1017

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## Abstract Using the whole-cell patch-clamp technique, we investigated the influence of extracellular pH and zinc ions (Zn2+) on the steady-state inactivation of Kv1.3 channels expressed in human lymphocytes. The obtained data showed that lowering the extracellular pH from 7.35 to 6.8 shifted the