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Effects of Certain Mono-, Di- and Trivalent Metal Cations on the K+-stimulated p-Nitrophenyl Phosphatase in Rat Brain

โœ Scribed by Bansal, S. K. ;Murthy, R. C. ;Chandra, S. V.


Book ID
114800251
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
228 KB
Volume
53
Category
Article
ISSN
0001-6683

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The effect of MnZ+, a divalent metal, on the enzyme K+-p-nitrophenyl phosphatase (K+-PNPPase) was studied in rat brain. The metal was found to be a moderate inhibitor of the enzyme, with an Is0 of approximately 4 8 0 ~~. The inhibition was pH dependent, but not temperature dependent. On measurement