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Effects of cereal alkylresorcinols on human platelet thromboxane production

✍ Scribed by P. Hengtrakul; M. Mathias; K. Lorenz

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
537 KB
Volume
2
Category
Article
ISSN
0955-2863

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini