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Effects of Ceramide on Aggrecanase Activity in Rabbit Articular Cartilage

✍ Scribed by Massimo Sabatini; Marie Thomas; Christine Deschamps; Christophe Lesur; Gaëlle Rolland; Guillaume de Nanteuil; Jacqueline Bonnet


Book ID
115587991
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
158 KB
Volume
283
Category
Article
ISSN
0006-291X

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✍ Jürgen Steinmeyer; Jens Kordelle; Henning Stürz 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 145 KB 👁 1 views

## Abstract Tetracyclines were reported to slow down the progression of cartilage damage both in an animal model of osteoarthritis (OA) and in humans. In search for the underlying mechanisms we examined whether tetracyclines possess an inhibitory potential on the activity of aggrecanases and inflam