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Effects of CD4+and CD8+T cells in tumor-bearing mice on antibody production

✍ Scribed by Motomu Shimizu; Takao Iwaguchi

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
469 KB
Volume
38
Category
Article
ISSN
0340-7004

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta