Effects of catecholamines on behavior
โ Scribed by Dr. Clara Torda
- Book ID
- 102910534
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 545 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
The potential for at least partial reversible transition of aggressionโ and anxietyโtype symptomatology suggested searching for a potential biochemical link between subโcellular mechanisms involved in the execution of aggression and anxiety. The effects of norepinephrine combined with dopamine and of epinephrine on these two types of behavior were tested. Responses to footโshock were used to test aggression, extinction of avoidance response was used to test anxietyโtype behavior. The results suggested that one of the possible links between the intracerebral processes responsible for execution of aggressionโ and anxietyโtype behaviors is transmethylation of norepinephrine and/or dopamine to epinephrine.
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Avoidance conditioning during pregnancy, changes in caretaker behavior during lactation, and changes in offspring catecholamine levels and behavior were investigated in C57BL/6J mice. Three equal groups of mice were employed. One group was avoidance conditioned prior to pregnancy and continued to av