## Abstract Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline due to neuronal loss and neural network dysfunction. It has been postulated that progressive neuronal loss in AD is consequence of the neurotoxic properties of the amyloid‐β peptide (Aβ). In the p
✦ LIBER ✦
Effects of Capsule Yi-Zhi on Learning and Memory Disorder and β-Amyloid Peptide Induced Neurotoxicity in Rats
✍ Scribed by Xu Jiang-Ping; Wu Hang-Yu; Li Lin; Sun Li Sha
- Book ID
- 109105648
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 41 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1080-563X
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## Abstract Studies with in‐vitro‐cultured neurons treated with amyloid‐β (Aβ) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)‐specific apoptotic pat