Effects of calcium channel antagonists on the corpora allata of adult male loreyi leafworm Mythimna loreyi: Juvenile hormone acids release and intracellular calcium level
✍ Scribed by Yi-Chun Hsieh; Err-Lieh Hsu; Ying-Shing Chow; Rong Kou
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 148 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0739-4462
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✦ Synopsis
The effects of voltage-dependent calcium channel (VDCC) antagonists and the non-specific calcium channel antagonists on both juvenile hormone acids (JHA) release and cytosolic free calcium concentration ([Ca2+]i) are investigated in the corpora allata (CA) of the adult males loreyi leafworm Mythimna loreyi. The VDCC antagonists used in this study are: the L-type antagonists diltiazem, nifedipine, and verapamil, the N-type antagonist omega-Conotoxin (CgTx) GVIA, the N- and P/Q-type antagonist omega-CgTx MVIIC, and the T-type antagonist amiloride. The non-specific calcium channel antagonists used in this study were cadmium (Cd2+), cobalt (Co2+), nickle (Ni2+), and lanthanum (La3+). The results show that both the DHPs-sensitive L-type antagonist nifedipine and the N-type antagonist omega-CgTx GVIA were able to inhibit JHA release, but only omega-CgTx GVIA was able to reduce the [Ca2+]i. Among the non-specific calcium channel antagonists, Cd2+ is the most potent in reducing JHA release but without obvious effect on the [Ca2+]i, La3+ significantly increases the [Ca2+]i but without effect on JHA release.