Effects of Calcitonin and Parathyroid Hormone on Calcification of Primary Cultures of Chicken Growth Plate Chondrocytes
β Scribed by Yoshinori Ishikawa; Licia N. Y. Wu; Brian R. Genge; Fackson Mwale; Dr. Roy E. Wuthier
- Book ID
- 119984319
- Publisher
- American Society for Bone and Mineral Research
- Year
- 1997
- Tongue
- English
- Weight
- 885 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0884-0431
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## Abstract Parathyroid hormoneβrelated peptide (PTHrP) and parathyroid hormone (PTH) have similar biological effects in vitro that are mediated through the PTH receptor. PTH receptors have been demonstrated in the zone of provisional calcification and the hypertrophic zone of the cartilaginous gro
Parathyroid hormone (PTH) binds specifically to the hypertrophic region of growth plate cartilage [16]. This specific binding suggests a role for this hormone in chondrocyte maturation. Enzymatically isolated chick articular and growth plate chondrocytes grown in monolayer culture were used to assay