## Background: P53 mutations are an early event in the multistep progression of gastric carcinoma. these mutations are often present in dysplastic and intestinal metaplastic gastric epithelium. however, the presence of immunohistochemically detectable p53 protein and p53 mutations in nondysplastic/
Effects of cagA+ and cagA– strains of Helicobacter pylori on the human gastric mucus layer thickness
✍ Scribed by MOHAMMED S AL-MARHOON; SHEILA NUNN; ROGER W SOAMES
- Book ID
- 108950310
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 134 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0815-9319
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## Abstract Infection with __Helicobacter pylori (H. pylori),__ especially CagA+ strains, has been associated with an increased risk of noncardia gastric adenocarcinoma. The relationship with junctional cancer (adenocarcinomas of the esophagus and gastric cardia combined) has not been adequately in
The incidence rates of gastric cardia and esophageal adenocarcinomas are increasing, but data suggest that carriage of cagA ؉ Helicobacter pylori strains may protect against development of Barrett's esophagus and esophageal adenocarcinoma. Our aims were to examine the relationship between pre-malign