College students (12 female, 12 male) were assigned to either higher caffeine user (HCU) or lower caffeine user (LCU) groups based on a caffeine usage survey. Prior to testing, subjects ingested either placebo or 195 or 325 mg caffeine. They then performed a visual vigilance task measuring response
Effects of caffeine or diphenhydramine on visual vigilance
β Scribed by Bernard J. Fine; John L. Kobrick; Harris R. Lieberman; Brent Marlowe; Robert H. Riley; William J. Tharion
- Book ID
- 105510325
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 674 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0033-3158
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## Abstract Single doses of caffeine (250 mg, 500 mg) or placebo were administered doubleβblind to healthy volunteer subjects (__n__ = 12), using a fully balanced crossover design (Williams square) with 1βweek washout. Assessments were made predrug, and at 45 min and 165 min postβdrug administratio
Caffeine is the most widely consumed stimulant to counter sleep-loss effects. While the pharmacokinetics of caffeine in the body is well-understood, its alertness-restoring effects are still not well characterized. In fact, mathematical models capable of predicting the effects of varying doses of ca