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Effects of Ca2+ and calmodulin on cyclic nucleotide metabolism in neurosecretosomes isolated from ox neurohypophyses

✍ Scribed by Darlene A. Dartt; Christian Torp-Pedersen; Niels A. Thorn

Book ID
118866832
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
463 KB
Volume
204
Category
Article
ISSN
0006-8993

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The effect of regucalcin, a calcium-binding protein isolated from rat liver cytosol, on Ca2+/calmodulin-dependent cyclic nucleotide (AMP) phosphodiesterase activity in rat liver cytosol was investigated. The addition of Ca2+ (50 microM) and calmodulin 160 U/ml in the enzyme reaction mixture caused a