Effects of Ca and H2O2 added to RPMI on the fretting corrosion of Ti6Al4V

✍ Scribed by Montague, Amy ;Merritt, Katharine ;Brown, Stanley ;Payer, Joe

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 776 KB
• Volume: 32
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/(sici)1097-4636(199612)32:4<519::aid-jbm4>3.0.co;2-u

✦ Synopsis

Titanium and its alloys have demonstrated considerable success in various surgical procedures including orthopedic, dental, and cardiovascular surgery. However, particulate debris from corrosion and wear is present in a considerable quantity in tissue local to the implant. This study evaluated the effect of Ca, since it is present in both serum and bone, and H202, since it is produced through local inflammation, on the amount of titanium release. Four sets of Ti6A14V plates and Ti6A14V screws were used. Each set was designated to one of four solutions: RPMI (cell culture growth media), RPMI with CaCl,, RPMI with CaC03, and RPMI with H202. A fretter was used to cause corrosion by creating micromotion between two screws and a two-hole plate of Ti6A14V. After fretting for 72 h, weight loss of the plate and screws and the amount of Ti and vanadium (V) in solution was used to assess the amount of fretting corrosion which had occurred. Results of weight loss and Ti in solution indicated that the presence of H202 increased the amount of particulate debris produced in RPMI as compared with RPMI alone. The addition of CaC1, to RPMI also increased both weight loss and Ti in solution compared with RPMI alone. The addition of CaC03, however, did not give values significantly different from RPMI alone. Comparison of weight loss and Ti in solution indicated that the increase in fretting