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Effects of c-KIT mutations on expression of the RUNX1/RUNX1T1 fusion transcript in t(8;21)-positive acute myeloid leukemia patients

✍ Scribed by Park, Sang Hyuk; Chi, Hyun-Sook; Cho, Young-Uk; Jang, Seongsoo; Park, Chan-Jeoung


Book ID
121656389
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
341 KB
Volume
37
Category
Article
ISSN
0145-2126

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## Abstract The t(1;21)(p36;q22) is a recurrent chromosome abnormality associated with therapy‐related acute myeloid leukemia (AML). Although involvement of __RUNX1__ has been detected by fluorescence in situ hybridization analysis, the partner gene has not been reported previously. We identified a