Prostaglandins of the E (PGE) series have long been considered ''catabolic'' hormones, but recent data suggest that they may be secreted in critically ill patients to counteract stress hormones, stimulating protein synthesis. Their use is under scrutiny to improve hepatic microcirculation and as cyt
Effects of branched-chain amino acids on nitrogen metabolism in patients with cirrhosis
β Scribed by Fredrick L. Weber Jr.; Brenda S. Bagby; Lucilla Licate; Steven G. Kelsen
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 906 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0270-9139
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Zinc deficiency is common in cirrhosis and has been tent is common in patients with advanced cirrhosis, involved in the altered nitrogen metabolism. In this particularly of alcohol origin, 2 but the biochemical basis study, we measured the effects of zinc supplementation for zinc deficiency is still
To test the hypothesis that hyperinsulinism is responsible for reduced branched-chain amino acids in cirrhotics, plasma amino acids were sequentially determined in 8 controls and 8 matched cirrhotics during continuous i.v. insulin infusion. An artificial endocrine pancreas which infused glucose was
Branched-chain amino acids (BCAA) are known to improve hepatic encephalopathy as well as protein malnutrition in cirrhosis. However, such effects in acute hepatic failure (AHF) remain to be elucidated. The current study was conducted to investigate whether BCAA improves protein metabolism in AHF. AH
ture of 21 to 24ΠC, and were kept as little disturbed as possible during sity, Ulm, Germany. the entire investigation. Monitoring was performed using automatic