Effects of Bovine Platelet-Poor Plasma on the Proliferation of Normal and Transformed BALB/c 3T3 Cells
✍ Scribed by Walker Wharton and John E. Estes
- Book ID
- 125618418
- Publisher
- Society for In Vitro Biology
- Year
- 1980
- Tongue
- English
- Weight
- 187 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1475-2689
- DOI
- 10.2307/4292380
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## Abstract Benzo[a]pyrene‐transformed Balb 3T3 cells (BP3T3) exhibit “normal” growth controls at low concentrations of serum. Epidermal growth factor (EGF) stimulates DNA synthesis and cell division in both Balb 3T3 and BP3T3 cells at physiological concentrations. The growth response of BP3T3 cell
## Abstract Platelet‐derived growth factor (PDGF) and platelet‐poor plasma, which lacks PDGF, both induce a rapid increase in the rate of total protein synthesis within quiescent, density‐arrested Balb/c‐3T3 cells. This stimulation of protein synthesis is associated with an increased aggregation of