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Effects of bisphosphonate on experimental jaw metastasis model in nude mice

โœ Scribed by A Sasaki; A Nishiyama; R.E Alcalde; D.J Lim; H Mese; S Nakayama; S Yokoyama; T Matsumura

Book ID
114394365
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
226 KB
Volume
35
Category
Article
ISSN
1368-8375

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Effect of a newly developed bisphosphona
Effect of a newly developed bisphosphonate, YH529, on osteolytic bone metastases in nude mice
โœ Akira Sasaki; Kazuyuki Kitamura; Rafael E. Alcalde; Toshimitsu Tanaka; Atushi Su ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 288 KB ๐Ÿ‘ 2 views

YH529, [1-hydroxy-2-(imidazo [1,2-a] pyridin-3-yl) ethylidene]-bisphosphonic acid monohydrate, is a newly developed third-generation bisphosphonate with a potent inhibitory activity toward osteoclastic bone resorption. The primary cellular mechanism of osteolysis associated with metastatic cancer is