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Effects of bile acids on rat hepatic microsomal type I 11β-hydroxysteroid dehydrogenase

✍ Scribed by Yorio Maeda; Seiji Naganuma; Ichiro Niina; Akio Shinohara; Chihiro Koshimoto; Kazuhiro Kondo; Kazuo Chijiiwa


Book ID
116892410
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
906 KB
Volume
75
Category
Article
ISSN
0039-128X

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Renal sodium retention and potassium loss occur early, in many instances in the preascitic state of cirrhosis, an observation that cannot be fully explained by increased aldosterone concentrations. We therefore hypothesize that 11␤-hydroxysteroid dehydrogenase 2 (11␤-HSD2), which protects mineraloco