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Effects of benzene and its metabolites on global DNA methylation in human normal hepatic l02 cells

✍ Scribed by Junjie Hu; Huimin Ma; Wenbing Zhang; Zhiqing Yu; Guoying Sheng; Jiamo Fu


Book ID
112221800
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
363 KB
Volume
29
Category
Article
ISSN
1520-4081

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The DNA-damaging ability of benzene and its metabolites on peripheral blood mononuclear cells (PBMC) has been investigated by using the alkaline comet assay. The PBMC were incubated with different compounds in two different media for 2 and 24 hr at concentrations that did not affect cell viability a