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Effects of baclofen on dopamine metabolism and interaction with neuroleptic effects

✍ Scribed by Peter C. Waldmeier; Laurent Maitre

Book ID: 118322984
Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 772 KB
Volume: 47
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(78)90390-4

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Baclofen, the parachlorophenyl analog of GABA, was found to induce catalepsy and to inhibit the traction response in mice. However, baclofen pretreatment, instead of antagonizing methamphetamine stereotypy and apomorphine-induced cage climbing behavior, was found to potentiate these behaviors, there

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