Effects of Axotomy and Testosterone on Androgen Receptor mRNA Expression in Hamster Facial Motoneurons
β Scribed by Susan M. Drengler; Robert J. Handa; Kathryn J. Jones
- Book ID
- 115606580
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 201 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0014-4886
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π SIMILAR VOLUMES
We have previously demonstrated that systemic administration of testosterone increases the rate of axonal regeneration following facial nerve crush in adult male hamsters. In the present study, the molecular mechanisms by which androgens could enhance axonal regeneration were examined at a cellular
## Abstract Rubrospinal motoneurons (RSMN) represent a population of androgen receptorβexpressing central motoneurons with limited regenerative potential relative to their peripheral counterparts. A key determinant of regenerative capability lies in the nucleolar reaction of injured neurons. To dat