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Effects of arsenic trioxide on cell death, reactive oxygen species and glutathione levels in different cell types

✍ Scribed by Park,

Book ID: 120383848
Publisher: Spandidos Publications Ltd
Year: 2009
Tongue: English
Weight: 368 KB
Volume: 25
Category: Article
ISSN: 1107-3756
DOI: 10.3892/ijmm_00000321

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## Abstract The observation that genistein may behave as a pro‐oxidant agent lead us to examine the capacity of this isoflavone to modulate the toxicity of the oxidation‐sensitive anti‐leukemic agent arsenic trioxide (ATO), and for comparison other anti‐tumor drugs. Co‐treatment with genistein incr