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Effects of Apocynin and Natural Antioxidant from Spinach on Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Induction in Lipopolysaccharide-Induced Hepatic Injury in Rat

✍ Scribed by Lomnitski, Liat ;Foley, Julie F. ;Grossman, Shlomo ;Shaul, Varda Ben ;Maronpot, Robert R. ;Moomaw, Cindy R. ;Carbonatto, Michela ;Nyska, Abraham

Book ID
110754831
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
231 KB
Volume
87
Category
Article
ISSN
0901-9928

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## Abstract The inhibitory effects of inotilone and methylinotilone on the induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase‐2 (COX‐2) in murine RAW 264.7 cells activated with LPS were investigated. The results show that both hydroxyl groups on the benzene ring of the inotilone