Antiviral effects of antisense RNA on he
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Wakita, Takaji; Moradpour, Darius; Tokushihge, Katsutoshi; Wands, Jack R.
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Article
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1999
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John Wiley and Sons
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English
β 227 KB
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We developed approaches using antisense RNA to inhibit hepatitis C virus (HCV) RNA translation and HCV core protein expression. An HCV genotype 1b cDNA comprising nt 1-1321 or a fusion construct consisting of HCV (nt 1-584) and luciferase cDNAs were inserted downstream of T7 and CMV promoter sequenc