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Effects of antihypertensive drugs on activities of ion pumps and autocrine of angiotensin II in spontaneously hypertensive rats

โœ Scribed by Qianhui Shang; Yuhuang Guo; Qin Wu; Qianfeng Jiang


Book ID
116550461
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
76 KB
Volume
152
Category
Article
ISSN
0167-5273

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โœ Albert Defelice; Harlan Lape; Patrick Horan; Richard Frering; Armand Brousseau; ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 833 KB

This study of spontaneously hypertensive (SH) rats documents oral antihypertensive activity of the vasodilator Ofornine@, an anthranilamide whose effect was sustained, at least in part, by suppression of compensatory renal and neurohumoral responses. Doses of 2.5 to 100 mg/kg p.0. reduced systolic b