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Effects of antihistaminics on naloxone-induced withdrawal in morphine-dependent mice

✍ Scribed by Juan-Carlos Leza; Ignacio Lizasoain; Pedro Lorenzo

Publisher
Springer
Year
1990
Tongue
English
Weight
626 KB
Volume
102
Category
Article
ISSN
0033-3158

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In this study, the effect of l-dopa and bromocriptine on morphine withdrawal syndrome was compared. Both l-dopa (125, 250 mg/kg, i.p.) and low doses of bromocriptine (0.04, 0.08 mg/kg, i.p.) potentiated naloxone-induced morphine withdrawal symptoms such as jumping, climbing and rearing in mice. High