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Effects of anticonvulsants on GLUT1-mediated glucose transport in GLUT1 deficiency syndrome in vitro

✍ Scribed by Jörg Klepper,Anne Flörcken,Jorge Fischbarg,Thomas Voit

Book ID
113042615
Publisher
Springer
Year
2003
Tongue
English
Weight
309 KB
Volume
162
Category
Article
ISSN
0340-6997

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## Abstract Anticonvulsant sodium valproate interferes with brain glucose metabolism. The mechanism underlying such metabolic disturbance is unclear. We tested the hypothesis that sodium valproate interferes with cellular glucose transport with a focus on Glut1 since glucose transport across the bl