Effects of angiotensin II on insulin receptor binding and mRNA levels in normal and diabetic rats
β Scribed by L. A. Sechi; C. A. Griffin; L. Zingaro; J.-P. Valentin; E. Bartoli; M. Schambelan
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 215 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The effect of metformin on hepatocyte insulin receptor binding was examined in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice. In normal mice, chronic administration of metformin (60 mg X kg-1 X day-1 for 50 weeks) increased the number of low affinity receptors by 148%.
Brain injury has been prevented recently by systemic administration of human insulin-like growth factor-I (hIGF-I). It is widely believed that protein neurotrophic factors do not enter the brain from blood, and the mechanism by which circulating hIGF-I may be neuroprotective is uncertain. This inves
Involvement of complications is considered to be one of the major factors in the prognosis of diabetes mellitus (DM). Recent studies indicate that most diabetic complications such as nephropathy and hypertension are vascularoriginated. ReninΒ±angiotensin involvement, especially changes in ACE activi