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Effects of analogs of 1,25(OH)2Vitamin D3on the proliferation and differentiation of the human chronic myelogenous leukemia cell line, RWLeu-4

✍ Scribed by Jeffrey W. Clark; Marshall R. Posner; Jean M. Marsella; Anabel Santos; Milan Uskokovic; Charles Eil; Stephen R. Lasky


Book ID
112535668
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
555 KB
Volume
118
Category
Article
ISSN
1432-1335

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In addition to a role in calcium and phosphate homeostasis other vitamin D receptor (VDR) mediated effects have been discovered during the past few years for the biologically active metabolite of vitamin D, 1,25(OH)2D 3. An antiproliferative, differentiation-inducing effect on nonmalignant and neopl