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Effects of an androgenic derivate over estrogen and progesterone receptors of malignant mammary tumours experimentally induced with dimethylbenz(a)anthracene

โœ Scribed by E. Escrich; MC. Ruiz de Villa; J. Murillo; E. Domlnguez; S. Saez


Book ID
116006859
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
197 KB
Volume
28
Category
Article
ISSN
0022-4731

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The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10