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Effects of an acidic beverage (Coca-Cola) on absorption of ketoconazole

โœ Scribed by Chin, T. W.; Loeb, M.; Fong, I. W.


Book ID
115500211
Publisher
American Society for Microbiology
Year
1995
Tongue
English
Weight
325 KB
Volume
39
Category
Article
ISSN
0066-4804

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## Abstract The changes in pharmacokinetics of DAโ€8159 by omeprazole with respect to inhibition of CYP3A1/2 in rats were evaluated. After oral administration of DAโ€8159 at dose of 30 mg/kg to rats pretreated with oral omeprazole at 30 mg/kg for 1 week, the total area under the plasma concentrationโ€“