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Effects of amiodarone administration during pregnancy on neonatal thyroid function and subsequent neurodevelopment

✍ Scribed by Bartalena, L.; Bogazzi, F.; Braverman, L. E.; Martino, E.

Book ID
125334758
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
129 KB
Volume
24
Category
Article
ISSN
0391-4097

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A single dose of 40 mg/kg of N-nitrosoethylurea (ENU) was administered to BDVI rats on the 16th day of pregnancy. The first generation descendants (F1) were mated on a brother-to-sister system to produce a second generation (F2) which was then mated to produce a third generation. A high incidence of