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Effects of amifostine on perfused isolated rat heart and on acute doxorubicin-induced cardiotoxicity

✍ Scribed by Pierre Nazeyrollas; Alain Prévost; Nathalie Baccard; Leslie Manot; Philippe Devillier; Hervé Millart

Publisher
Springer
Year
1999
Tongue
English
Weight
158 KB
Volume
43
Category
Article
ISSN
0344-5704

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## Abstract The prevention of doxorubicin (DXR)‐induced cardiotoxicity may be helpful to improve future DXR therapy. The aim of this study was to investigate the cardio‐protective effects of caffeic acid phenethyl ester (CAPE), an antioxidant agent, on DXR‐induced cardiotoxicity. Rats were divided