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Effects of aldose reductase inhibition with tolrestat on diabetic retinopathy in a six months double blind trial

โœ Scribed by Joop M. A. Van Gerven; Johan P. Boot; Herman H. P. J. Lemkes; Jaap A. Van Best


Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
718 KB
Volume
87
Category
Article
ISSN
0012-4486

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Aldose reductase inhibition with imirest
โœ A. L. Carrington; C. B. Ettlinger; N. A. Calcutt; D. R. Tomlinson ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 633 KB

This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p < 0.05). These changes occurred in the absence of any deficit