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Effects of alanosine and hadacidin on enzymes using aspartic acid as a metabolite

✍ Scribed by Margaret C. Laue; Berwin P. Yip; Frederic B. Rudolph


Book ID
115773409
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
278 KB
Volume
26
Category
Article
ISSN
0006-2952

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A novel synergistic effect of alanosine
✍ Radhey S. Gupta πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 536 KB

## Abstract A novel synergistic effect of the antitumor agent alanosine (2‐amino‐3‐(hydroxynitrosoamino) propionic acid), which specifically inhibits the enzyme adenylosuccinate synthetase (ASS) and guanine on the growth of Chinese hamster ovary (CHO) cells and human diploid fibroblasts (HDF) has b