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Effects of aging on the induction of experimental systemic lupus erythematosus (SLE) in mice

✍ Scribed by Yaron Tomer; Shlomo Mendlovic; Tania Kukulansky; Edna Mozes; Yehuda Shoenfeld; Amiela Globerson


Book ID
119026364
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
650 KB
Volume
58
Category
Article
ISSN
0047-6374

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Systemic lupus erythematosus (SLE) has been induced in C3H.SW mice by their immunization with a human monoclonal anti-DNA antibody that bears a common idiotype-16/6 Id. Following immunization, high levels of murine anti-l6/6 and anti-anti-l6/6 antibodies were detected in the sera of the immunized mi