## Abstract A significant biochemical change that takes place in intervertebral disc degeneration is the loss of proteoglycans in the nucleus pulposus. Proteoglycans attract fluid, which works to reduce mechanical stresses in the solid matrix of the nucleus and provide a hydrostatic pressure to the
Effects of aging and degeneration on the mechanical behavior of lumbar L4–5 segments—A finite element study
✍ Scribed by Zhitao Xiao; Liya Wang; He Gong; Xizheng Zhang
- Book ID
- 116323838
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 66 KB
- Volume
- 47
- Category
- Article
- ISSN
- 8756-3282
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract This study tested the hypothesis that changes in the morphology and composition of the nucleus pulposus with age and degeneration have associated changes in its mechanical properties. A torsional shear experiment was used to determine viscoelastic shear properties of cylindrical samples
## Abstract A simplified finite element model of the human lumbar intervertebral disc was utilized for understanding nucleus pulposus implant mechanics. The model was used to assess the effect of nucleus implant parameter variations on the resulting compressive biomechanics of the lumbar anterior c