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Effects of age and the CYP2D6∗10 allele on the plasma haloperidol concentration/dose ratio

✍ Scribed by Koichi Ohara; Shigeru Tanabu; Kazuhisa Ishibashi; Keiko Ikemoto; Kimiko Yoshida; Haruo Shibuya

Book ID
117449061
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
145 KB
Volume
27
Category
Article
ISSN
0278-5846

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## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the