It was found that DL-lactate, acetate, pyruvate, succinate, fnmarate, malate, oxalacetate and L-aspartate stimulated considerably the production of the antitumor L-asparaginase EC-2 by a colieinogenie strain of E. coli in Tryptone medium. While in the absence of these stimulative substances enzyme p
Effects of aeration and of corn steep concentration on L-asparaginase production inEscherichia coli
โ Scribed by J. Netrval
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 133 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1432-0614
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The microorganism Aspergihs niger CCRC 3 1494 can produce an extracellular glucosyltransferase (GTase, EC 2.4.1.24) with a high transglucosylating activity. The maximal enzyme production occurred at initial maltose concentration of 40 g 1-l. The microorganism was also grown in a 5-liter jar fermente
## Abstract Asparaginases isolated from __Escherichia coli__ and __Erwinia carotovora__ are effective in the treatment of acute lymphoblastic leukemia in man. During treatment with either of these enzymes, patients frequently experience pronounced toxicity, including liver and pancreatic dysfunctio