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Effects of adrenaline on the acquisition and maintenance of ethanol preference in a taste conditioning paradigm

✍ Scribed by Carmen Guaza; Sara Borrell; Jose Borrell

Publisher: Springer
Year: 1986
Tongue: English
Weight: 465 KB
Volume: 90
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00179187

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✦ Synopsis

The effects of subcutaneous adrenaline administration on preference for ethanol (2.5% solution) have been investigated, using a two-bottle choice situation. Administration of the amine (50 gg/kg) immediately after the conditioning session significantly attenuated ethanol preference. Adrenaline treatment (10, 50 or 100 gg/kg) prior to the first retention test induced a significant reduction in ethanol preference. When the amine was injected prior to conditioning only the dose of 100 gg/kg reduced later ethanol preference. Our results indicate that systemically administered adrenaline impairs the acquisition of preference to a weak ethanol solution. It is suggested that this effect of the amine may be linked to interference with consolidation of memory and retrieval processes.

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