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Effects of adrenalectomy and aryl hydrocarbon receptor antagonists on teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J mice

✍ Scribed by Dongsun Park; Sunhee Shin; Jeong Hee Jeon; Ja Young Jang; Byong-il Choi; Yun-Bae Kim


Book ID
113875197
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
70 KB
Volume
24
Category
Article
ISSN
0890-6238

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),