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Effects of administration of ciliary neurotrophic factor on normal motor and sensory peripheral nerves in vivo

โœ Scribed by Stuart C. Apfel; Joseph C. Arezzo; Mary Moran; John A. Kessler


Book ID
115803738
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
489 KB
Volume
604
Category
Article
ISSN
0006-8993

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We investigated the histological effects of ciliary neurotrophic factor on degenerating motor neurons, their axons, and skeletal muscles in 68 wobbler mice with motor neuron disease. Treatment consisted of recombinant rat or human ciliary neurotrophic factor (or a vehicle solution), 1-mg/kg subcutan