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Effects of Additives on the Stability of Recombinant Human Factor XIII during Freeze-Drying and Storage in the Dried Solid

✍ Scribed by Lotte Kreilgaard; Sven Frokjaer; James M. Flink; Theodore W. Randolph; John F. Carpenter

Book ID
115567376
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
219 KB
Volume
360
Category
Article
ISSN
0003-9861

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Effect of pH on stability of recombinant
Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations
✍ Shouvik Roy; Ian Henderson; Rajiv Nayar; Theodore W. Randolph; John F. Carpenter πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 201 KB πŸ‘ 1 views

The purpose of this study was to evaluate the importance of prelyophilization solution pH on the stability of botulinum neurotoxin, serotype A (rBoNTA(H c )). This understanding is of significant importance for proteins such as rBoNTA(H c ), a potential constituent of a multivalent vaccine product.