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Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain

✍ Scribed by Paul Cumming; Pedro Rosa-Neto; Hideaki Watanabe; Donald Smith; Dirk Bender; Paul B.S Clarke; Albert Gjedde


Book ID
119586044
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
266 KB
Volume
19
Category
Article
ISSN
1053-8119

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## Abstract The D~2~ receptors exist in either the high‐ or low‐affinity state with respect to agonists, and while agonists bind preferentially to the high‐affinity state, antagonists do not distinguish between the two states. [^11^C]‐(+)‐PHNO is a PET D~2~ __agonist__ radioligand and therefore pro