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Effects of acute GR38032F (odansetron), a 5-HT3 receptor antagonist, on dopamine and serotonin metabolism in mesolimbic and nigrostriatal dopaminergic neurons

✍ Scribed by Markku Koulo; Birgitta Sjöholm; Jaakko Lappalainen; Raimo Virtanen


Book ID
115882074
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
270 KB
Volume
169
Category
Article
ISSN
0014-2999

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GR38032F, a 5HT3receptor antagonist, in
✍ Michel Marty; Jean P. Droz; Pierre Pouillart; Bernard Paule; Nils Brion; Jacques 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 330 KB

A total of 28 patients receiving cancer chemotherapy with cisplatin-containing regimens (70-120 mg/ m 2) participated in an evaluation of the efficacy and safety of GR38032F for the prevention of acute nausea and vomiting. GR38032F, a 5HT3 receptor antagonist, was given 30 min prior to cisplatin as