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Effects of acute fluoxetine on extracellular serotonin levels in the raphe: an in vivo microdialysis study

✍ Scribed by Isabelle Malagié; Anne-Cécile Trillat; Christian Jacquot; Alain M. Gardier

Book ID
115890559
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
468 KB
Volume
286
Category
Article
ISSN
0014-2999

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Fluoxetine (FLU) rapidly enhances extracellular (EC) serotonin (5-HT) in rodent brain, whereas the antidepressant effects of this drug in humans are typically not observed for 2-3 weeks. Thus, the effects of chronic oral FLU administration on neocortical and hippocampal EC 5-HT, and on caudate EC 5-